Independent oversight is an essential part of ensuring the rights and welfare of people who participate in clinical research. Institutional Review Board (IRB) oversight is required for research involving human subjects, and Institutional Biosafety Committee (IBC) review is required for research involving recombinant or synthetic nucleic acid molecules.
While the role of the IRB is better known to most clinical researchers, the IBC has crucial responsibilities to protect those involved in gene transfer research. The primary role of the IRB is to protect all aspects of the rights and welfare of research subjects. The primary role of the IBC in clinical trials is to protect study staff and the general public, as well as research subjects, specifically from risks associated with gene transfer agents.
Considering their overlapping yet separate missions, the IRB and the IBC have the potential to cooperate and effect synergistic improvement in the efficiency, rigor, and quality of the review of proposed research.
Download this whitepaper to learn more about the integration of IRB and IBC Review.